Locked-in syndrome: A neurological
disorder characterized by complete paralysis of voluntary muscles in all
parts of the body except for those that control eye movement. The locked-in
syndrome is usually a complication of a cerebrovascular accident (a stroke)
in the base of the pons in the brainstem. The patient is alert and fully
conscious but cannot move. Only vertical movements of the eyes and blinking
are possible.
There is no cure for locked-in syndrome,
nor is there a standard course of treatment. Functional neuromuscular stimulation
may help activate some paralyzed muscles. Several devices to help communication
are available. Other treatment is symptomatic and supportive. The prognosis
for those with locked-in syndrome is poor. The majority of patients do
not regain function.